PD-1/PD-L1-IN-26

SKU: orb1744753

Description

PD-1/PD-L1-IN-26 is a potent small molecule inhibitor of the PD-1/PD-L1 interaction with an IC50 of 38 nM. It is applied in cancer immunotherapy research, where it has been shown to enhance antitumor immunity by promoting CD4+ T cell infiltration in tumor models, supporting its use in both in vitro and in vivo studies.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2966090-78-6
• MW: 752.89
• Formula: C₄₃H₅₂N₄O₈
• SMILES: CC1=C(C=CC=C1C2=CC(=CC=C2)OCCCN3CCC(CC3)CO)COC4=CC(=C(C=C4)CNC(CO)(CO)CO)OCC5=NN=C(O5)C6=CC=CC=C6
• Target: PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163409052