PD-1/PD-L1-IN-23

SKU: orb1744749

Description

PD-1/PD-L1-IN-23 is an orally bioavailable ester prodrug of the benzooxadiazole-based PD-1/PD-L1 inhibitor L7. It demonstrates potent in vitro binding inhibition and has shown significant antitumor efficacy in syngeneic mouse models and studies using PD-L1 humanized mice.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2597056-04-5
• MW: 703.41
• Formula: C₃₂H₃₀BrCl₂N₃O₆
• SMILES: O(CC1=CC=2C(C=C1)=NON2)C3=C(CN[C@@H](C(OCC)=O)CO)C=C(Cl)C(OCC4=C(Br)C(=CC=C4)C5=CC=CC=C5)=C3.Cl
• Target: PD-1/PD-L1,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164185614