PD-161570

SKU: orb1305719

Description

PD-161570

Research Area

Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 192705-80-9
• MW: 532.51
• Purity: 99.23%
• Formula: C₂₆H₃₅Cl₂N₇O
• SMILES: CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl
• Target: FGFR,EGFR,PDGFR,TGF-beta/Smad,Src
• Solubility: DMSO:30 mg/mL (56.34 mM);Ethanol:< 53.25 mg/mL

Bioactivity

• Target IC50:
  FGFR1 autophosphorylation:622 nM|EGFR:240 nM|c-Src:44 nM|FGFR1:39.9 nM (IC50)|FGFR1:42 nM (Ki)|PDGFR:310 nM|PDGFRβ:262 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Src, TGF-β Receptor, PDGFR, PDGFRβ, Transforming growth factor beta receptors, tyrosine, Inhibitor, kinases, inhibit, PD161570, PD-161570, PD 161570, Platelet-derived growth factor receptor, HER1, EGFR, ErbB-1, Epidermal growth factor receptor, FGFR1, FGFR, Fibroblast growth factor receptor, disease, c-Src, cardiovascular, anti-proliferation, anti-cancer, angiogenesis, ATP-competitive, autophosphorylation

Compound Identifiers

PubChem CID

5328135