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PCLX-001

SKU: orb2900765

Description

PCLX-001 is an orally acitve, small-molecule, dual N-myristoyltransferase (NMT) inhibitor, with IC50s of 5 nM (NMT1) and 8 nM (NMT2), respectively. PCLX-001 exhibits anti-tumor activity and inhibits early B-cell receptor (BCR) signaling, can be used to B-cell malignancies research.

Images & Validation

Key Properties

CAS Number1215011-08-7
MW537.51
Purity>98% (HPLC)
FormulaC24H30Cl2N6O2S
SMILESN(S(=O)(=O)C1=C(Cl)C=C(C=C1Cl)C=2C=C(N=CC2)N3CCNCC3)C=4C(CC(C)C)=NN(C)C4C
SolubilityIn Vitro: DMSO : 10 mg/mL (18.60 mM; Ultrasonic (<60°C)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • PCLX-001 [orb1686248]

    99.60% (May vary between batches)

    1215011-08-7

    537.51

    C24H30Cl2N6O2S

    25 mg, 50 mg, 200 mg, 5 mg, 1 mg, 10 mg, 100 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Available Sizes

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500 mg
2 mg
$ 530.00
5 mg
$ 820.00
10 mg
$ 1,120.00
25 mg
$ 1,720.00
50 mg
$ 2,280.00
100 mg
$ 3,020.00