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PBE-AMF

SKU: orb2664545

Description

PBE-AMF is a prodrug that activates hydrogen peroxide, selectively inhibiting the proliferation of aggressive MDA-MB-231 breast cancer cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells. Its anticancer mechanism involves disrupting DNA synthesis, depleting ATP, inducing apoptosis, and causing cell cycle arrest, making it a candidate for in vitro oncology research.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

TargetDNA/RNA Synthesis,Reactive Oxygen Species,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information