PBA-1105 TFA

SKU: orb2945002

Description

PBA-1105 TFA is an AUTOTAC molecule that selectively targets misfolded proteins by binding their hydrophobic regions, inducing p62 self-oligomerization to drive their autophagic degradation. It enhances clearance of Ub-bound aggregates and is a valuable research tool for studying autophagy mechanisms in cellular and in vivo models of protein aggregation diseases.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• MW: 754.832
• Formula: C₄₁H₄₉F₃N₂O₈
• SMILES: C1=CC=C(C=C1)CCCC(=O)NCCOCCOCCOCCNCC2=CC(=C(C=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4.C(=O)(C(F)(F)F)O
• Target: Autophagy,AUTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676794