PB28

SKU: orb1704256

Description

PB28 dihydrochloride is a dual sigma-2 receptor agonist and sigma-1 antagonist with demonstrated anti-tumor and anti-SARS-CoV-2 research applications. It suppresses renal cancer cell proliferation and invasion via PI3K-AKT-mTOR pathway modulation and induces non-caspase-dependent apoptosis in neuroblastoma cells by inhibiting ER calcium release.

Research Area

Neuroscience

Key Properties

• CAS Number: 172907-03-8
• MW: 443.5
• Purity: >98%
• Formula: C₂₄H₃₈N₂O·2HCl
• SMILES: COC1=CC=CC2=C1CCCC2CCCN3CCN(C4CCCCC4)CC3.Cl.Cl
• Target: ER/Golgi
• Solubility: Soluble in DMSO (up to 25 mg/ml) or in Water (up to 5 mg/ml)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46861545