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PB118

SKU: orb1944542

Description

PB118 is a potent and selective HDAC6 inhibitor (IC50 = 5.6 nM) with multimodal activity relevant to Alzheimer's disease research. It promotes amyloid-beta clearance, stabilizes microtubules via tubulin acetylation, reduces neuroinflammation, and lowers phospho-tau levels in cellular and in vivo models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

MW314.35
FormulaC18H19FN2O2
SMILESO=C(NO)C1=CC(F)=C(CN2CCCCC3=CC=CC=C32)C=C1
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information