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PAT-347

SKU: orb1739205

Description

PAT-347 is a potent small molecule inhibitor of Autotaxin (ATX), the enzyme that produces lysophosphatidic acid (LPA) from lysophosphatidylcholine. By blocking this key enzymatic step, it disrupts the ATX-LPA signaling axis, a validated target for research in fibrosis, cancer biology, and inflammatory diseases, as evidenced in various in vitro and in vivo studies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1689554-51-5
MW538.99
FormulaC28H21ClF2N2O3S
SMILESC(CN1C=2C(C(SC3=C(F)C(C(O)=O)=CC=C3)=C1C)=CC=C(Cl)C2F)(=O)N4CC5(C=6C4=CC=CC6)CC5
TargetPDE,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information