PAT-1251 Hydrochloride

SKU: orb1708936

Description

PAT-1251 Hydrochloride is a potent, selective, and orally bioavailable small molecule inhibitor targeting lysyl oxidase-like 2 (LOXL2), with IC50 values of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It is a valuable research tool for investigating the role of LOXL2 in fibrotic diseases, cancer metastasis, and cardiovascular remodeling in both cellular and animal models.

Research Area

Neuroscience

Key Properties

• CAS Number: 2098884-53-6
• MW: 435.8
• Formula: C₁₈H₁₈ClF₄N₃O₃
• SMILES: O(C=1N=C(C(F)(F)F)C=C(CN)C1)C2=CC(C(=O)N3C[C@@H](F)[C@H](O)C3)=CC=C2.Cl
• Target: Monoamine Oxidase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132253084