PAT-048

SKU: orb1706845

Description

PAT-048 is a potent and selective autotaxin inhibitor (IC50=20 nM) shown to reduce dermal fibrosis in vivo and suppress IL-6 mRNA. It is a valuable research tool for studying lysophosphatidic acid (LPA) signaling in fibrotic diseases, including skin and lung fibrosis models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1359983-15-5
• MW: 461.91
• Formula: C₂₂H₁₈ClF₂N₃O₂S
• SMILES: CC=1N(C=2C(C1SC3=C(F)C(C(O)=O)=CC=C3)=CC=C(Cl)C2F)C4=CN(CCC)N=C4
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

66765263