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Parsaclisib

SKU: orb1309280

Description

Parsaclisib

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1426698-88-5
MW432.88
Purity99.02% (May vary between batches)
FormulaC20H22ClFN6O2
SMILESCCOc1c(cc(Cl)c(F)c1[C@@H]1CNC(=O)C1)[C@H](C)n1nc(C)c2c(N)ncnc12
TargetPI3K
SolubilityDMSO:122 mg/mL (281.83 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.24 mM)

Bioactivity

Target IC50
PI3Kδ:1 nM (at 1 mM ATP)
In Vitro
Parsaclisib displays significant activity with IC50 values ranging from 0.2 to 2 nM in B and T cell proliferation aaasys. Parsaclisib inhibits proliferation of several DLBCL and MCL cell lines in vitro (EC50 < 10 nM).

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, malignancies, Parsaclisib, inhibit, INCB 050465, INCB-050465, INCB050465, B-cell, relapsed, Phosphoinositide 3-kinase, PI3K, PI3Kδ, PI3Kδ, 1 mM ATP, refractory

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 190.00
5 mg
$ 370.00
1 ml x 10 mM (in DMSO)
$ 400.00
10 mg
$ 530.00
25 mg
$ 890.00
50 mg
$ 1,210.00
100 mg
$ 1,620.00
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