PARP1/BRD4-IN-1

SKU: orb1686571

Description

PARP1/BRD4-IN-1 is a potent dual inhibitor of PARP1 (IC50=49 nM) and BRD4 (IC50=202 nM). It suppresses their expression and activity, demonstrating synergistic anti-proliferative effects in pancreatic cancer cell models in vitro, supporting its use in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2758117-74-5
• MW: 506.56
• Formula: C₂₉H₂₆N₆O₃
• SMILES: C(N1C(C=2C(N(C)C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4)C=5NC=6C(N5)=CC=CC6C(N)=O
• Target: DNA/RNA Synthesis,Others,PARP,Apoptosis,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162717039