PARP1/2-IN-3

SKU: orb2664576

Description

PARP1/2-IN-3 (Compound 29) is a potent, orally bioavailable dual PARP1/2 inhibitor with sub-nanomolar IC50 values. It effectively inhibits the proliferation of various PARP inhibitor-resistant cancer cell lines in vitro and demonstrates in vivo anti-tumor efficacy in mouse models, supporting its use in oncology research.

Key Properties

• CAS Number: 3032451-58-1
• MW: 484.48
• Formula: C₂₆H₂₁FN₆O₃
• SMILES: O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CC5=NN=C(C=6OC(=CC6)C)N5CC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172419470