PARP1-IN-50

SKU: orb3174647

Description

PARP1-IN-50 is a selective, orally active PARP-1 inhibitor with an IC50 of 64.98 nM. It inhibits PAR formation and induces DNA double-strand breaks, resulting in DNA damage. PARP1-IN-50 can cause G2/M phase arrest and apoptosis (apoptosis) in cancer cells, demonstrating significant antiproliferative activity against various cancer cell lines. This compound is useful in cancer research, including studies on breast cancer.

Key Properties

• CAS Number: 2255341-36-5
• MW: 662.42
• Formula: C₂₂H₂₆Br₂N₆O₄S₂
• SMILES: S=C(N)NN=CC1=CC(Br)=C(OCCCCOC2=C(Br)C=C(C=NNC(=S)N)C=C2OC)C(OC)=C1
• Target: CDK,Apoptosis,Bcl-2 Family,PARP,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK,Apoptosis,Bcl-2 Family,PARP,DNA/RNA Synthesis