PARP1-IN-39

SKU: orb3135411

Description

PARP1-IN-39 is an inhibitor of PARP1, with an IC50 value of 0.22 nM. In human breast cancer cells, its IC50 is 1.57 nM. PARP1-IN-39 is applicable for studying cancers associated with DNA repair deficiencies, such as breast, ovarian, pancreatic, and prostate cancers, particularly those with BRCA1/2 mutations.

Research Area

Cell Biology

Key Properties

• CAS Number: 3054988-47-2
• MW: 508.46
• Formula: C₂₄H₁₉F₃N₈O₂
• SMILES: O=C(NCC)C1=NC(F)=C(C=C1)N2N=C3C(=C2)CN(C3)CC4=CC=C5C(NC(=O)C6=C(F)C=NN56)=C4F
• Target: PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PARP