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PARP1-IN-27

SKU: orb2665398

Description

PARP1-IN-27 (Compound 9B) is a potent dual PARP1/2 inhibitor with low nanomolar IC50 values. It demonstrates anti-proliferative activity in BRCA-mutant cell lines by inducing DNA damage, ROS, G2/M arrest, and apoptosis, supporting its use in oncology research for studying DNA repair mechanisms and synthetic lethality.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction

Images & Validation

Key Properties

MW313.28
FormulaC17H12FNO4
TargetApoptosis|||PARP|||Reactive Oxygen Species

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information