PARP1-IN-14

SKU: orb1944221

Description

PARP1-IN-14 (compound 19k) is a highly potent PARP1 inhibitor with an IC50 of 0.6 nM. It exhibits strong antiproliferative activity in BRCA-deficient cell lines such as MDA-MB-436 and Capan-1. This inhibitor is a valuable chemical probe for studying DNA damage response and synthetic lethality in cancer research models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2098639-70-2
• MW: 525.53
• Formula: C₂₈H₂₄FN₇O₃
• SMILES: CC1N2C(=NN=C2CN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)C1)C=6N=C(OC)C=CC6
• Target: Apoptosis,PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

140912416