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PARP1 degrader 1

SKU: orb3181792

Description

PARP1 degrader1 (Compound 2c) is a relatively potent PARP1HyT degrader with an intracellular PARP-1 DC50 of 618 nM. It is also a conjugate of HyT-Olaparib. PARP1 degrader1 induces UPR/autophagy, promoting the degradation of PARP-1, and can be utilized in cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

TargetPARP,Autophagy

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information