PARP-2/1-IN-2

• Catalog Number: orb1744617
• Category: Small Molecules
• Description: PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].
• CAS Number: 912444-01-0
• Purity: 98.00%
• MW: 244.29
• SMILES: C(N)(=O)C1=C2C(N=C(N2)[C@]3(C)CCCN3)=CC=C1
• Formula: C₁₃H₁₆N₄O
• Biological Activity: PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.