PARP-1/2-IN-1

SKU: orb1687536

Description

PARP-1-/2-IN-1 is a highly potent dual inhibitor of PARP-1 and PARP-2 with IC50 values of 0.51 nM and 23.11 nM, respectively. This compound is a valuable chemical tool for investigating PARP biology in cancer research, including studies of DNA damage response and synthetic lethality in cellular and animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1903744-45-5
• MW: 438.49
• Formula: C₂₄H₂₇FN₄O₃
• SMILES: C(N1C=2C(C(=O)NC1=O)=CC=CC2)C3=CC(C(=O)N4C[C@@H](CC)N(CC)CC4)=C(F)C=C3
• Target: PARP,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

130292366