Paroxetine hydrochloride hemihydrate

SKU: orb1706889

Description

Paroxetine hydrochloride hemihydrate, marketed as Paxil, is a selective serotonin reuptake inhibitor (SSRI). This compound is widely used in neuroscience and pharmacology research to study depression, anxiety disorders, and serotonin signaling pathways in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 110429-35-1
• MW: 749.67
• Purity: >99.99% (May vary between batches)
• Formula: C₃₈H₄₄Cl₂F₂N₂O₇
• SMILES: FC(C=C1)=CC=C1[C@H](CCNC2)[C@@H]2COC3=CC=C(OCO4)C4=C3.FC(C=C5)=CC=C5[C@H](CCNC6)[C@@H]6COC7=CC=C(OCO8)C8=C7.Cl.O.Cl
• Target: Autophagy,GRK,5-HT Receptor,Serotonin Transporter
• Solubility: DMSO:45 mg/mL (60.03 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.67 mM)

Bioactivity

• Target IC50:
  GRK2:14 μM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Paxil, Paroxetine hydrochloride Hemihydrate, Paroxetine Hydrochloride, Paroxetine HCl, 5HTReceptor, 5HT Receptor, serotonin reuptake, Seroxat

Compound Identifiers

PubChem CID

5282487