Parishin C

SKU: orb1685022

Description

Parishin C, a phenolic glycoside and principal constituent of Gastrodia elata, exhibits antioxidant properties. Research applications include in vitro studies of oxidative stress and neuroprotection, as well as in vivo models investigating its potential therapeutic effects.

Research Area

Metabolism Research

Key Properties

• CAS Number: 174972-80-6
• MW: 728.65
• Purity: 99.91%
• Formula: C₃₂H₄₀O₁₉
• SMILES: OC[C@H]1O[C@@H](Oc2ccc(COC(=O)CC(O)(CC(=O)OCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3)C(O)=O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
• Target: Antioxidant
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.37 mM);H2O:33.3 mg/mL (45.7 mM);DMSO:242.5 mg/mL (332.81 mM)

Bioactivity

• In Vivo:
  In vivo, parishin C (20 mg/kg) prevents Aβ42-induced inhibition of long-term potentiation (LTP) in rats. Parishin is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 1.54 nM; EC50 = 34 nM for [35S]GTPγS binding) that reverses phencyclidine-induced increases in immobility time in the forced swim test, phencyclidine-induced decreases in interaction time in the social interaction test, and phencyclidine-induced impairments in visual recognition of a novel object in mice.

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antioxidant, inhibit, Parishin C, Inhibitor

Compound Identifiers

PubChem CID

10676408