Paris saponin VII

SKU: orb1303178

Description

Paris saponin VII (Dioscini) is a bioactive steroidal saponin that suppresses cellular proliferation. It is utilized in cancer research, demonstrating anti-tumor activity in both in vitro cell culture studies and in vivo animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 68124-04-9
• MW: 1031.18
• Purity: 99.83% (May vary between batches)
• Formula: C₅₁H₈₂O₂₁
• SMILES: C[C@@H]1[C@@]2(CC[C@@H](C)CO2)O[C@H]2C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]3(C)[C@@]12O)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
• Target: P-gp,Autophagy,Akt,PARP,Bcl-2 Family,p38 MAPK,Apoptosis,Caspase
• Solubility: DMSO:125 mg/mL (121.22 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.94 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Chonglou Saponin VII, CD243, Cluster of differentiation 243, Caspase, Dioscinin, Apoptosis, Autophagy, Bcl-2 Family, Akt, ABCB1, Multidrug resistance protein 1, inhibit, PARP, Paris saponin VII, Paris saponin-VII, MDR1, Inhibitor, Protein kinase B, poly ADP ribose polymerase, p38 MAPK, p38MAPK, Polyphyllin-VII, P-gp (P-glycoprotein), P-gp, Pgp, P-glycoprotein, PKB

Compound Identifiers

PubChem CID

176233