PARG-IN-6

SKU: orb3135157

Description

PARG-IN-6 (Compound 2) is an orally bioavailable PARG inhibitor with an IC50 of 0.3 nM. It exhibits significant anticancer activity against cancer cells, with an IC50 of 0.0368 μM for HCC1395 cells. PARG-IN-6 shows potential for research in colon cancer, appendiceal cancer, and pancreatic cancer.

Research Area

Cell Biology

Key Properties

• CAS Number: 3083070-66-7
• MW: 647.69
• Formula: C₂₄H₂₅F₄N₇O₄S₃
• SMILES: N#CC1(NS(=O)(=O)C2=CC=3C(=NN(C3C(=C2F)C4=C(C)CN(CC4)S(=O)(=O)C(C)C)C)C5=NN=C(S5)C(F)(F)F)CC1
• Target: Poly(ADP-ribose) Glycohydrolase (PARG)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Poly(ADP-ribose) Glycohydrolase (PARG)