PAR4 antagonist 6

SKU: orb2665423

Description

Compound 12 is a potent small molecule antagonist of protease-activated receptor 4 (PAR4), demonstrating inhibitory activity with IC50 values of 134 nM for human PAR4 and 150 nM for mouse PAR4. This tool compound is suitable for investigating PAR4-mediated signaling in thrombosis, inflammation, and cancer research across both in vitro cellular assays and in vivo disease models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 344.32
• Formula: C₁₆H₁₄F₂N₆O
• Target: Protease-activated Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Protease-activated Receptor