PAR3 (1-6) (human)

SKU: orb3142267

Description

PAR3 (1-6) is a synthetic peptide agonist of Protease-Activated Receptor 1 (PAR1), corresponding to residues 1-6 of the extracellular tethered ligand sequence from human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates the p42/44 MAPK signaling pathway in fibroblasts expressing PAR1 but not PAR3. This activation can be inhibited by the PAR1 antagonist RWJ 56110.1.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: Protease-activated Receptor
• CAS Number: 320347-28-2
• MW: 647.72
• Formula: C₂₉H₄₅N₉O₈
• SMILES: C([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H]([C@@H](C)O)N)=O)=O)CCCNC(=N)N)=O)=O)C)(=O)N2[C@H](C(O)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Protease-activated Receptor