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PAR2 modulator-1

SKU: orb3174638

Description

PAR2modulator-1 (Compound C781) is an antagonist of the protease-activated receptor 2 (PAR2). It specifically inhibits the PAR2-dependent MAPK signaling pathway with an IC50 value of 8.5 μM. PAR2modulator-1 can effectively block pain responses triggered by PAR2 agonists. This compound is useful for research in inflammation, immunology, and neurological disorders, including chronic pain and asthma.

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Key Properties

CAS Number2378159-28-3
MW515.66
FormulaC27H41N5O5
SMILESC(=O)(N1C2N([C@@H](CC(C)C)C(=O)N(CC3CCNCC3)C2)C(=O)[C@@H](NC(CC(C)C)=O)C1)C4=CC=CO4
TargetProtease-activated Receptor,p38 MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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PAR2 modulator-1 (orb3174638)

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