PapRIV TFA

• Catalog Number: orb1980068
• Category: Small Molecules
• Description: PapRIV, a quorum-sensing heptapeptide derived from B. cereus, undergoes synthesis as a 48-amino acid polypeptide. This compound is secreted and then extracellularly processed by NprB proteases into its active form. At concentrations ranging from 1-25 µM, PapRIV triggers the production of IL-6 and TNF-α, as well as NF-κB translocation, specifically in BV-2 microglia cells.
• Purity: 98.00%
• MW: 843.90
• Biological Activity: PapRIV, a quorum-sensing heptapeptide derived from B. cereus, undergoes synthesis as a 48-amino acid polypeptide. This compound is secreted and then extracellularly processed by NprB proteases into its active form. At concentrations ranging from 1-25 µM, PapRIV triggers the production of IL-6 and TNF-α, as well as NF-κB translocation, specifically in BV-2 microglia cells.
• Formula: C₃₈H₅₃N₉O₁₃.XCF₃COOH
• SMILES: O=C([C@@H](N)CO)N[C@H](C(N[C@@H](CC(C)C)C(N1CCC[C@H]1C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(O)=O)CC3=CNC=N3)=O)CCC(O)=O)=O)=O)=O)=O)CC(O)=O.OC(C(F)(F)F)=O
• Storage: -20°C
• Note: For research use only