PaPE-1

SKU: orb2815313

Description

PaPE-1 is a pathway-selective estrogen receptor modulator that activates beneficial membrane-initiated signaling while avoiding classical nuclear pathways. It demonstrates neuroprotective effects in vitro by countering Aβ-induced apoptosis, modulating key apoptotic gene expression (e.g., reducing Bax and increasing Bcl2), and shows potential for research in neurodegenerative disease models.

Key Properties

• CAS Number: 2107327-36-4
• MW: 254.32
• Formula: C₁₇H₁₈O₂
• SMILES: O[C@@H]1C=2C(=CC(=CC2)C3=CC(C)=C(O)C(C)=C3)CC1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

123133800