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Pan-RAS-IN-4

SKU: orb2564462

Description

Pan-RAS-IN-4 (compound 2) is a potent small molecule inhibitor of KRAS G12D with an IC50 below 100 nM. It is a valuable research tool for investigating RAS-driven oncology in both cellular and animal models, supporting the development of targeted cancer therapies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number3024060-23-6
MW698.80
FormulaC38H44F2N8O3
SMILESC(OC1=NC(=C2C(=N1)CN(CC2)C=3C4=C(C=C(O)C3)C=CC(F)=C4CC)N5CC6=C7C(=NN6CCC5)C(=O)N(C)CC7)[C@@]89N(C[C@H](F)C8)CCC9
TargetRas,Kras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information