Cart summary

You have no items in your shopping cart.

pan-KRAS-IN-6

SKU: orb2564692

Description

Pan-KRAS-IN-6 (compound 12) is a potent pan-KRAS inhibitor, with IC50 values of 9.79 nM for Kras G12D and 6.03 nM for Kras G12V.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number3033565-36-2
MW635.10
FormulaC29H30ClF3N6O3S
SMILESC(OC=1N=C(C2=C(N1)C(F)=C(C(Cl)=C2)C3=C4C(SC(N)=N4)=C(F)C=C3)N5CC(C)(O)COCC5)[C@@]67N(C[C@H](F)C6)CCC7
TargetRas,Kras

Storage & Handling

Storage-20°C
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

pan-KRAS-IN-6 (orb2564692)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%