pan-KRAS-IN-5

SKU: orb2565583

Description

Pan-KRAS-IN-5 (compound 15a) is a small molecule pan-KRAS inhibitor that functions by targeting 5'-UTR RNA G-quadruplexes to suppress KRAS translation. It demonstrates anti-cancer activity in vitro by inducing cell cycle arrest and apoptosis in KRAS-driven cancer cell lines.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 3027172-23-9
• MW: 642.55
• Formula: C₃₁H₃₆FIN₄O₂
• SMILES: C[N+]=1C2=C(C=C(F)C(NCCN3CCCC3)=C2)C=CC1/C=C/C4=CC=5C(OC4=O)=CC(N(CC)CC)=CC5.[I-]
• Target: Apoptosis,Kras,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170836277