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pan-KRAS-IN-13

SKU: orb3134245

Description

pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, exhibiting IC50 values of 2.75 nM and 2.89 nM for its G12D and G12V mutations, respectively.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number3033637-76-9
MW616.63
FormulaC33H31F3N6O3
SMILESFC1=C2C=3C(N4[C@@](CCOC3N=C1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(CNCC4)[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2
TargetRas

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information