pan-HER-IN-1

SKU: orb1687991

Description

pan-HER-IN-1 (Compound C5) is an orally bioavailable, irreversible pan-HER inhibitor with low nanomolar potency against EGFR, HER2, HER4, and mutant EGFR (T790M/L858R). It induces apoptosis and demonstrates antitumor efficacy in both cellular assays and in vivo research models, making it a useful tool for studying oncogenic HER signaling pathways.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1639040-94-0
• MW: 408.25
• Formula: C₁₉H₁₄BrN₅O
• SMILES: N(C=1C2=C(C=CC(NC(C=C)=O)=C2)N=CN1)C=3C=C4C(=CC3)NC=C4Br
• Target: Others,EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163408815