Pamiparib maleate

SKU: orb1699723

Description

Pamiparib (BGB-290) is a potent and selective PARP inhibitor that disrupts base-excision repair, leading to DNA damage accumulation and apoptosis. It is widely used in preclinical oncology research, demonstrating antitumor activity in both in vitro cell assays and in vivo xenograft models of cancers with homologous recombination deficiencies.

Research Area

Cell Biology

Key Properties

• CAS Number: 2086689-94-1
• MW: 944.859
• Formula: C₄₄H₄₂F₂N₈O₁₄
• SMILES: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
• Target: Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168012555