Pamiparib hydrate

SKU: orb1739365

Description

Pamiparib (BGB-290) is a potent and selective PARP inhibitor that disrupts DNA repair via the base-excision repair pathway, leading to genomic instability and apoptosis. It is widely used in cancer research to study synthetic lethality in BRCA-deficient models and to potentiate the effects of DNA-damaging agents in both in vitro and in vivo experiments.

Key Properties

• CAS Number: 1858211-28-5
• MW: 352.36
• Formula: C₁₆H₂₁FN₄O₄
• SMILES: O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138679246