Pamidronate disodium pentahydrate

SKU: orb1307001

Description

Pamidronate disodium pentahydrate is a bisphosphonate drug that potently inhibits osteoclast-mediated bone resorption. It is widely used in osteoporosis research and in vitro studies to investigate mechanisms of bone metabolism and in vivo models of hypercalcemia and Paget's disease.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 109552-15-0
• MW: 371.13
• Purity: 99.84% (May vary between batches)
• Formula: C₃H₂₁NNa₂O₁₂P₂
• SMILES: OC(P(O)(O)=O)(CCN)P(O)(O)=O.O.O.O.O.[Na+].[Na+].O
• Target: Others,RANKL/RANK,TLR,Wnt/beta-catenin,Antibacterial
• Solubility: H2O:7.14 mg/mL (19.24 mM);DMSO:insoluble

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Pamidronate, Pamidronate disodium, Pamidronate disodium Pentahydrate, Pamidronate disodium pentahydrate

Compound Identifiers

PubChem CID

131842124