Pam3CSK4 TFA (112208-00-1 free base)

SKU: orb1296767

Description

Pam3CSK4 TFA is a potent synthetic lipopeptide agonist of Toll-like receptors 1 and 2 (TLR1/2), with a reported EC50 of 0.47 ng/mL for human TLR1/2. It is widely used in immunology research to stimulate innate immune responses, both in vitro and in vivo, for studying inflammation, vaccine adjuvants, and macrophage activation.

Research Area

Immunology & Inflammation

Key Properties

• Target: TLR
• CAS Number: 112208-01-2
• MW: 1852.33
• Purity: 96.40% (May vary between batches)
• Formula: C₈₇H₁₅₉F₉N₁₀O₁₉S
• SMILES: O=C(N[C@@H](CCCCN)C(=O)O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CCCCCCCCCCCCCCC)CSCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC.FC(F)(F)C(=O)O.FC(F)(F)C(=O)O.FC(F)(F)C(=O)O

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

112208-00-1, 112208-00-1 free base, Inhibitor, inhibit, Pam3CSK4, Pam3CSK4 TFA, Pam3CSK4 TFA (112208 00 1 free base), Pam3CSK4 TFA (112208001 free base), Pam-3CSK4 TFA (112208-00-1 free base), Pam3Cys-Ser-(Lys)4 TFA, TLR, TLR2/1, Toll-like Receptor (TLR)

Compound Identifiers

PubChem CID

155977631