Paltusotine

SKU: orb1297944

Description

Paltusotine is an orally bioavailable, nonpeptide small molecule agonist of the somatostatin type 2 (SST2) receptor. It is used in research to investigate the pharmacological control of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels, relevant for acromegaly studies in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2172870-89-0
• MW: 456.49
• Purity: 99.91% (May vary between batches)
• Formula: C₂₇H₂₂F₂N₄O
• SMILES: NC1CCN(CC1)c1c(cnc2ccc(cc12)-c1cccc(C#N)c1O)-c1cc(F)cc(F)c1
• Target: Somatostatin
• Solubility: DMSO:20 mg/mL (43.81 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CRN 00808, CRN00808, CRN-00808, Inhibitor, IGF-1, inhibit, Paltusotine, orally, SSTRs, SSTR, SST2, Somatostatin Receptor

Compound Identifiers

PubChem CID

134168328