Paltimatrectinib

SKU: orb1687597

Description

Paltimatrectinib (PBI-200) is a potent and selective TrkA tyrosine kinase inhibitor used in cancer research. It has demonstrated activity in preclinical studies of bladder, breast, and colorectal cancers, showing potential in both in vitro and in vivo experimental models.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 2353522-15-1
• MW: 434.37
• Purity: 99.96% (May vary between batches)
• Formula: C₂₀H₁₅F₅N₆
• SMILES: [H][C@@]1(CCCN1c1ccn2ncc(-n3cc(cn3)C(F)(F)F)c2n1)c1cc(F)ccc1F
• Target: Tyrosinase,Trk receptor,Tyrosine Kinases
• Solubility: DMSO:10 mg/mL (23.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PBI-200, PPI-5278, Trk receptor, TrkA, Trkreceptor, Tyrosine Kinases, TyrosineKinases

Compound Identifiers

PubChem CID

155753054