Palbociclib orotate

SKU: orb2279138

Description

Palbociclib (PD 0332991) orotate is an orally bioavailable, selective CDK4/6 inhibitor (IC50: 11 and 16 nM, respectively). It potently inhibits proliferation and induces cell cycle arrest in vitro and shows efficacy in vivo models, supporting research in HR+/HER2- breast cancer and hepatocellular carcinoma.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2757498-64-7
• MW: 603.63
• Formula: C₂₉H₃₃N₉O₆
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK