PAI-1 Recombinant Protein

SKU: orb1230963

Description

PAI-1 Recombinant Protein

Research Area

Cancer Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• Source: E. coli
• Biological Activity: Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37˚C. Half maximal inhibition against 1.0 μg/mL of single chain tPA was obtained at a concentration of 2.0 μg/mL.
• Target: SERPINE1
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• Protein Sequence: MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGV ASVLAMLQLT TGGETQQQIQ AAMGFKIDDK GMAPALRHLY KELMGPWNKD EISTTDAIFV QRDLKLVQGF MPHFFRLFRS TVKQVDFSEV ERARFIINDW VKTHTKGMIS NLLGKGAVDQ LTRLVLVNAL YFNGQWKTPF PDSSTHRRLF HKSDGSTVSV PMMAQTNKFN YTEFTTPDGH YYDILELPYH GDTLSMFIAA PYEKEVPLSA LTNILSAQLI SHWKGNMTRL PRLLVLPKFS LETEVDLRKP LENLGMTDMF RQFQADFTSL SDQEPLHVAQ ALQKVKIEVN ESGTVASSST AVIVSARMAP EEIIMDRPFL FVVRHNPTGT VLFMGQVMEP

Storage & Handling

• Storage: The lyophilized PAI-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted PAI-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing PAI-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Form/Appearance: Lyophilized
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PAI, PAI1, PAI-1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, PAI

Quick Database Links

Gene Symbol

SERPINE1

UniProt

P05121

RefSeq (Protein):NP_000593.1