Pacritinib-d8

SKU: orb2281093

Description

Pacritinib-d8 is a deuterated analog of Pacritinib (CAS 937272-79-2), a potent and selective JAK2/FLT3 inhibitor with IC50 values of 23 and 22 nM, respectively. This compound is a valuable research tool for investigating myeloproliferative neoplasms and acute myeloid leukemia in both cellular and animal models.

Key Properties

• MW: 480.628
• Formula: C₂₈H₂₄D₈N₄O₃
• SMILES: [2H]C(C1([2H])[2H])([2H])C([2H])([2H])C([2H])([2H])N1CCOC(C=C2)=C(COC/C=C/COCC3=CC4=CC=C3)C=C2/N=C5NC4=CC=N\5

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653178