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PACMA 31

SKU: orb1303129

Description

PACMA 31

Images & Validation

Key Properties

CAS Number1401089-31-3
MW430.47
Purity99.92%
FormulaC21H22N2O6S
SMILESCCOC(=O)CNC(=O)C(N(C(=O)C#C)c1ccc(OC)cc1OC)c1cccs1
TargetOthers
SolubilityDMSO:100 mg/mL (232.3 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.29 mM)

Bioactivity

In Vivo
In human ovarian cancer mouse xenografts, PACMA 31 (20-200 mg/kg) i.p. or per os administration of significantly inhibited tumor growth by 85% and 65% At day 62, respectivel.
In Vitro
In OVCAR-8 cells, PACMA 31 (0-10 μM) potently inhibits colony formation in a dose-dependent manne.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

protein disulfide isomerase (PDI), toxicity, tumor, Inhibitor, inhibit, oral, ovarian, PACMA 31, PACMA31, PACMA-31, mice, athymic, bond, covalent, colony
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Key Properties

No computed properties available.

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Protocol Information

PACMA 31 (orb1303129)

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% Tween 80 +
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Available Sizes

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2 mg
$ 80.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 130.00
25 mg
$ 230.00
50 mg
$ 350.00
100 mg
$ 550.00
200 mg
$ 770.00
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