Pachypodol

SKU: orb1684346

Description

Pachypodol is a methoxyflavonoid from Pogostemon cablin with antioxidant and cytoprotective properties. It inhibits CaCo-2 colon cancer cell growth in vitro and, in neonatal rats, protects against anesthesia-induced neuroapoptosis via JNK/ERK modulation. It also exhibits PDGFRα kinase inhibitory activity in macrophages stimulated with STING agonists.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 33708-72-4
• MW: 344.32
• Purity: 99.82% (May vary between batches)
• Formula: C₁₈H₁₆O₇
• SMILES: COc1cc(O)c2c(c1)oc(-c1ccc(O)c(OC)c1)c(OC)c2=O
• Target: PERK,Antioxidant,Apoptosis,Nrf2
• Solubility: DMSO:80 mg/mL (232.34 mM)

Bioactivity

• In Vitro:
  Pachypodol, acting as a flavonol, is capable of inhibiting the growth of CaCo 2 colon cancer cell lines in vitro, and exhibits certain antioxidant and cytoprotective effects in HepG2 cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antifection, antioxidant, Pachypodol

Compound Identifiers

PubChem CID

5281677