p53-MDM2-IN-5

SKU: orb2564384

Description

p53-MDM2-IN-5 (5a) is a potent small molecule inhibitor of the p53-MDM2 interaction. It triggers apoptosis, autophagy, DNA damage, and S/G2/M phase cell cycle arrest, demonstrating antitumor efficacy in both cellular and animal model studies for cancer research.

Research Area

Cancer Biology; Cell Biology, Cell Biology

Key Properties

• CAS Number: 2750075-06-8
• MW: 974.57
• Formula: C₃₃H₃₇Cl₄F₂N₅O₆Pt
• SMILES: C(#N)[C@]1([C@H]([C@H](C(NC2=C(OC)C=C(C([O-][Pt+4]([O-]C(C)=O)([Cl-])([Cl-])([NH3])[NH3])=O)C=C2)=O)N[C@H]1CC(C)(C)C)C3=C(F)C(Cl)=CC=C3)C4=C(F)C=C(Cl)C=C4
• Target: Apoptosis,Autophagy,MDM-2/p53

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Autophagy,MDM-2/p53