p53 Activator 11

SKU: orb2565593

Description

P53 Activator 11 (A-1) is a potent small molecule activator of the p53 (Y220C) mutant, exhibiting an EC50 of 0.478 µM. It serves as a valuable chemical probe for investigating p53-dependent pathways in cancer biology, supporting both in vitro and in vivo oncology research.

Research Area

Cancer Biology, Cell Biology

Key Properties

• CAS Number: 2850211-42-4
• MW: 503.62
• Formula: C₂₆H₂₉N₇O₂S
• SMILES: C(#CCNC1=CC=C(S(N)(=O)=O)C=C1)C2=C(N3C(C(NC4CCN(C)CC4)=CC=C3)=N2)N5C=CC=C5
• Target: MDM-2/p53

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170453385