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p38 MAPK-IN-10

SKU: orb3136174

Description

p38 MAPK-IN-10 (Compound 4) is an orally active and potent inhibitor of p38 MAP kinase, with an IC50 of 570 nM. It shows promise for research into chronic inflammatory diseases, including rheumatoid arthritis and Crohn's disease.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number340041-97-6
MW305.31
FormulaC17H12FN5
SMILESFC1=CC=C(C=C1)C=2N=C3N=C(N)C=CN3C2C=4C=CN=CC4
Targetp38 MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information