P300-IN-6

SKU: orb3210785

Description

P300-IN-6 is an orally active inhibitor of the histone acetyltransferase (HAT) p300 domain, with an IC50 value of 7 nM in humans. It suppresses c-Myc expression, reduces H3K18ac and H3K27ac levels, and inhibits cancer cell proliferation. Additionally, P300-IN-6 hinders tumor growth in xenograft mouse models and is suitable for research in multiple myeloma.

Key Properties

• CAS Number: 3034595-62-2
• MW: 454.52
• Formula: C₂₆H₂₆N₆O₂
• SMILES: CN1C=2C(=CC=C(NC([C@H](NC[C@@H](C)C3=CC=C(C#N)C=C3)C4=CC=CC=C4)=O)N2)N(C)C1=O
• Target: c-Myc,Histone Acetyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

c-Myc,Histone Acetyltransferase